10 Best Laundry Detergents 2026 in the United States

Mrs. Meyer's Clean Day Liquid Laundry Detergent is a concentrated liquid formula designed to be both effective at cleaning and gentle on clothes. It uses plant-based ingredients and enzymes to tackle dirt and stains, making it a solid choice if you want reliable cleaning power. The detergent comes with a fresh Lemon Verbena scent, which is light and pleasant without being overpowering. With each 64-ounce bottle providing about 64 loads, the two-pack offers good value for regular household use. One of the standout features is its eco-friendly approach — the formula is biodegradable and cruelty-free, certified by Leaping Bunny, which is great if you prefer environmentally responsible products. It’s also compatible with both high-efficiency and traditional washing machines.

For those with sensitive skin, this detergent is generally gentle, though it does contain essential oils which some very sensitive users might want to be cautious about. While it performs well in stain removal, it may not be as strong on tough, set-in stains compared to some heavy-duty detergents. Mrs. Meyer's detergent is well suited for people looking for a natural, eco-conscious option with a nice scent, effective cleaning, and a gentle touch on fabrics.

ECOS Laundry Detergent Liquid is a plant-based, liquid detergent designed to handle up to 200 loads, making it quite concentrated and economical. It uses a lavender scent, which is pleasant but not overpowering, suitable for those who like a light fragrance on their clothes. The detergent is dermatologist-tested and hypoallergenic, which is great if you have sensitive skin or allergies. It avoids harsh chemicals like parabens, phosphates, and dyes, so it’s gentle on your skin and better for the environment.

Its formulation is pH-balanced and free from many common irritants, making it a safe choice for families, including those with children or skin sensitivities. ECOS is also eco-friendly, with EPA Safer Choice certification, and made in a way that supports sustainability, including being vegan and cruelty-free. The liquid form typically dissolves well in water and cleans effectively, though it may not be as strong on very tough stains compared to some specialized heavy-duty detergents.

For those who prioritize green cleaning and sensitive skin care over aggressive stain fighting, this detergent fits well. It serves as a solid option for anyone wanting an effective, environmentally responsible detergent with a mild, natural scent.

Gain Odor Defense Liquid Laundry Detergent is designed to provide a fresh scent and strong odor removal, specifically targeting tough smells rather than just masking them. It comes in a large 194 fl oz bottle, offering about 134 loads, which is convenient for frequent laundry users. The 'Super Fresh Blast' scent is noticeable and intended to last for weeks after washing, appealing to those who enjoy scented laundry.

This detergent works well in cold water and is compatible with both regular and high-efficiency washers, making it suitable for most households. Its 2-in-1 formula combines detergent with odor-fighting properties, eliminating the need for an additional product. While the focus is on odor elimination, users seeking heavy stain removal might consider other options better suited for that purpose.

The liquid form and standard concentration make it easy to measure and use without waste. This detergent is an excellent choice for users prioritizing odor elimination and a long-lasting fresh scent, particularly for those who wash often in cold water and prefer a straightforward, reliable product.